Col4a4 ELISA Kit for Mouse(Mus musculus) | EIAab.comCol4a4 ELISA Kit for Mouse(Mus musculus)

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Col4a4 (Gene name),

Collagen alpha-4(IV) chain (Protein name ), CO4A4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Col4a4;

Protein name:

Collagen alpha-4(IV) chain;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

There are six type IV collagen isoforms, alpha 1(IV)-alpha 6(IV), each of which can form a triple helix structure with 2 other chains to generate type IV collagen network. The alpha 3(IV) chain forms a triple helical protomer with alpha 4(IV) and alpha 5(IV); this triple helical structure dimerizes through NC1-NC1 domain interactions such that the alpha 3(IV), alpha 4(IV) and alpha 5(IV) chains of one protomer connect with the alpha 5(IV), alpha 4(IV) and alpha 3(IV) chains of the opposite protomer, respectively (By similarity). Associates with LAMB2 at the neuromuscular junction and in GBM.

Function:

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane Colocalizes with COL4A3 and COL4A5 in GBM, tubular basement membrane (TBM) and synaptic basal lamina.

Protein Attributes:

Sequence length:

1682

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1682:

LQFASGPSPD | TLKEVQAQRR | KISRCQVCMK | HS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9QZR9

SMR:

Q9QZR9

Pfam:

PF01413

UniGene:

Mm.40253

KEGG:

mmu:12829

Uniprot:

Q9QZR9

FOR

ELISA Kit for Mouse Collagen alpha-4(IV) chain

Cat.:

E9534h

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Manual:

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Packing:

96T

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ELISA Kit for Mouse Collagen alpha-4(IV) chain

Cat.:

E9534m

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Collagen alpha-4(IV) chain

Cat.:

E9534b

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Collagen alpha-4(IV) chain

MSDS:

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CLIA Kit for Mouse Collagen alpha-4(IV) chain

Cat.:

U9534b

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Collagen alpha-4(IV) chain

Cat.:

U9534m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse Collagen alpha-4(IV) chain

MSDS:

Please sign in first.

CLIA Kit for Mouse Collagen alpha-4(IV) chain

Cat.:

U9534h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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Polyclonal Antibody for Mouse Collagen alpha-4(IV) chain

Cat.:

P9534Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Collagen alpha-4(IV) chain

Cat.:

P9534Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Collagen alpha-4(IV) chain

Protein for Mouse Collagen alpha-4(IV) chain

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome."
Lu W. , Phillips C.L. , Killen P.D. , Hlaing T. , Harrison W.R. , Elder F.F.B. , Miner J.H. , Overbeek P.A. , Meisler M.H.
Genomics61:113-124(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Embryonic kidney.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
3.

"Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches."
Miner J.H. , Sanes J.R.
J. Cell Biol.127:879-891(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1371-1682 (ISOFORM 1);FUNCTION;ASSOCIATED WITH LAMB2;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: BALB/c.
tissue: Kidney.
4.

"Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo."
Miosge N. , Quondamatteo F. , Klenczar C. , Herken R.
J. Histochem. Cytochem.48:229-238(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
5.

"Collagen IV in the developing lens capsule."
Kelley P.B. , Sado Y. , Duncan M.K.
Matrix Biol.21:415-423(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE

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